Alpha-halocarboxylic acids and derivatives
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Filtered Search Results
Cayman Chemical Apamin trifluoroacetate salt
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An inhibitor of KCa2.2/SK2 channels (IC50s = 0.06-0.4 nM); selective for KCa2.2/SK2 channels over KCa2.1/SK1 and KCa2.3/SK3 channels (IC50s = 1-12 and 1-13 nM, respectively), as well as KCa3.1/SK4 channels at 1 µM but does inhibit Kv1.3 (IC50 = 13 nM); reduces CD8+ cell infiltration into the CNS and EAE severity, as well as increases peripheral blood levels of CD62L-, CD44L-, and CD44+ memory T cells, in mice; has commonly been used to determine the role of KCa/SK channels in various cells and tissues
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eMolecules Ambeed / 3-Chlorobenzoic acid / 5g / 490505816 / A132909 / / 535-80-8 / MFCD00002491 / 156.570 / C7H5ClO2
Ambeed / 3-Chlorobenzoic acid / 5g / 490505816 / A132909 / / 535-80-8 / MFCD00002491 / 156.570 / C7H5ClO2
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000410436 SODIUM IODOACETATE 10G
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Chem-Impex International, Inc. Dichloroacetic acid | MFCD00004223 | 100G
Dichloroacetic acid, MFCD00004223, 100G
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Chem-Impex International, Inc. Bromoacetic acid tert-butyl ester | 5292-43-3 | MFCD00000188 | 25G
Bromoacetic acid tert-butyl ester, 5292-43-3, MFCD00000188, 25G
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Medchemexpress LLC MEDCHEMEXPRESS LLC
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5000405905 HYALURONIC ACID SOD 5MG
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Chem-Impex International, Inc. Bromoacetic acid tert-butyl ester | 5292-43-3 | MFCD00000188 | 250G
Bromoacetic acid tert-butyl ester, 5292-43-3, MFCD00000188, 250G
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AdipoGen Bafilomycin B1
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Chemical. CAS 88899-56-3. Formula C44H65NO13. MW 815.9. Isolated from Streptomyces hygroscopicus. Macrolide antibiotic. Specific vacuolar-type H-ATPase inhibitor. Inhibitor of autophagic degradation by rising lysosomal pH and thus inactivating the lysosomal acid hydrolases. Antitrypanosomal and antileishmanial compound. Phytotoxic. Influences the cell wall biosynthesis of Asp. niger.
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Cayman Chemical K 41498 trifluoroacetate sal
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A peptide antagonist of CRF2α and CRF2β (Kis = 0.66 and 0.62 nM, respectively, in HEK293 cells expressing the human receptors); selective for CRF2α and CRF2β over CRF1 (Ki = 425 nM in HEK293 cells expressing the human receptor); prevents urocortin-induced hypotension in rats at 1.84 UG, i.v; intrathecal administration decreases the mechanical paw withdrawal threshold in a complete Freund's adjuvant-induced rat model of nociception at 0.075-0.5 µmol
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Cayman Chemical GGTI 298 trifluoroacetate sa
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A CAAX peptidomimetic that selectively inhibits geranylgeranyltransferase I; arrests human tumor cells (IC50 = 10 µM for A549 cells) in G0/G1 and induces apoptosis by inhibiting proteasome activity and up-regulating the expression of the cyclin-dependent kinase inhibitor p21
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DSK BIOPHARMA INC Methyl bromoacetate-2,2-d2 | 163886-16-6 | 154.99 g/mol | 5G
Methyl bromoacetate-2,2-d2 | 163886-16-6 | 154.99 g/mol | 5G
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Cambridge Isotope Laboratories ETHYL BROMOACETATE (1-13C, 99%), 5 G, 61203-71-2
ETHYL BROMOACETATE (1-13C, 99%), 5 G, 61203-71-2
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eMolecules ETHYL BROMOACETATE 25G
NC3859379 ETHYL BROMOACETATE 25G
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Chem-Impex International, Inc. ISOPROPYL TRIFLUOROACETATE
NC3861846 ISOPROPYL TRIFLUOROACETATE
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Cayman Chemical W146 trifluoroacetate salt
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An S1P1 receptor antagonist (Ki = 77 nM); selective for S1P1 over S1P2, S1P3, and S1P5 (Kis = >10 µM); prevents ligand-induced receptor internalization in CHO cells and inhibits ERK and Akt phosphorylation at 10 µM; increases AMD3100-induced KSL-HSPC entrance into mouse blood circulation from the bone marrow at 5 mg/kg in combination with AMD3100; disrupts the endothelial barrier and induces PMN neutrophil infiltration into the lungs and skin in an ovalbumin-induced mouse model of immune cell-mediated vascular injury at 10 UG intranasally or intradermally
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